<i>Isolona hexaloba</i> Engl. & Diels: Phytochemistry, Pharmacology and Future Directions: A Mini-Review

Lengbiye Moke; Gédéon Bongo; Kongumbeti Goga; Jeff Iteku; Inkoto Liyongo; Claudine Tshiama; Ngunde Ngunde; Koto-te-Nyiwa Ngbolua; Pius Mpiana

doi:doi:10.11648/j.plant.20180603.11

Isolona hexaloba Engl. & Diels: Phytochemistry, Pharmacology and Future Directions: A Mini-Review

Lengbiye Moke, Gédéon Bongo, Kongumbeti Goga, Jeff Iteku, Inkoto Liyongo, Claudine Tshiama, Ngunde Ngunde, Koto-te-Nyiwa Ngbolua, Pius Mpiana

Published in Plant (Volume 6, Issue 3)

Received: 9 June 2018 Accepted: 30 September 2018 Published: 29 October 2018

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Abstract

The aim of this review was to provide an updated knowledge on the Phytochemistry and Pharmacognosy of Isolona hexaloba Engl. & Diels. A literature search was conducted to obtain information about the phytochemistry and pharmacognosy of Isolona hexaloba from various electronic databases (PubMed Central, PubMed, Science Direct and Google scholar). The scientific name of this plant species was used as a keyword for the search, along with the terms phytochemistry and pharmacognosy. The chemical structures of the Isolona hexaloba and Isolona genus naturally occurring compounds were drawn using ChemBioDraw Ultra 12.0 software package. The findings revealed that this plant is traditionally used as a purgative and in treating sores, smoke from the bark as a strained muscle relaxant, infectious and parasitic pathologies, loss of appetite, rheumatism, intestinal cramps, headache, back pains, sexual weakness. This plant is reported to possess various biological properties like antioxidant, antimicrobial, antihyperglycemic, antileishmanial and antimalarial. These properties are due to the presence of numerous naturally occurring phytochemicals like flavonoids, alkaloids, tannins, saponins, reducting sugars, coumarins, terpenes and steroids. The present mini-review revealed that Isolona hexaloba Engl. & Diels is a good candidate for Tropical Plants Screening Research program for the development of lead compounds against genetic and parasitic diseases such as the evaluation of the anthelminthic activity.

Published in	Plant (Volume 6, Issue 3)
DOI	10.11648/j.plant.20180603.11
Page(s)	53-59
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Isolona hexaloba, Phytochemistry, Pharmacognosy, Anthelminthic Activity

References

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Lengbiye Moke, Gédéon Bongo, Kongumbeti Goga, Jeff Iteku, Inkoto Liyongo, et al. (2018). Isolona hexaloba Engl. & Diels: Phytochemistry, Pharmacology and Future Directions: A Mini-Review. Plant, 6(3), 53-59. https://doi.org/10.11648/j.plant.20180603.11

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ACS Style

Lengbiye Moke; Gédéon Bongo; Kongumbeti Goga; Jeff Iteku; Inkoto Liyongo, et al. Isolona hexaloba Engl. & Diels: Phytochemistry, Pharmacology and Future Directions: A Mini-Review. Plant. 2018, 6(3), 53-59. doi: 10.11648/j.plant.20180603.11

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AMA Style

Lengbiye Moke, Gédéon Bongo, Kongumbeti Goga, Jeff Iteku, Inkoto Liyongo, et al. Isolona hexaloba Engl. & Diels: Phytochemistry, Pharmacology and Future Directions: A Mini-Review. Plant. 2018;6(3):53-59. doi: 10.11648/j.plant.20180603.11

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@article{10.11648/j.plant.20180603.11,
  author = {Lengbiye Moke and Gédéon Bongo and Kongumbeti Goga and Jeff Iteku and Inkoto Liyongo and Claudine Tshiama and Ngunde Ngunde and Koto-te-Nyiwa Ngbolua and Pius Mpiana},
  title = {Isolona hexaloba Engl. & Diels: Phytochemistry, Pharmacology and Future Directions: A Mini-Review},
  journal = {Plant},
  volume = {6},
  number = {3},
  pages = {53-59},
  doi = {10.11648/j.plant.20180603.11},
  url = {https://doi.org/10.11648/j.plant.20180603.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.plant.20180603.11},
  abstract = {The aim of this review was to provide an updated knowledge on the Phytochemistry and Pharmacognosy of Isolona hexaloba Engl. & Diels. A literature search was conducted to obtain information about the phytochemistry and pharmacognosy of Isolona hexaloba from various electronic databases (PubMed Central, PubMed, Science Direct and Google scholar). The scientific name of this plant species was used as a keyword for the search, along with the terms phytochemistry and pharmacognosy. The chemical structures of the Isolona hexaloba and Isolona genus naturally occurring compounds were drawn using ChemBioDraw Ultra 12.0 software package. The findings revealed that this plant is traditionally used as a purgative and in treating sores, smoke from the bark as a strained muscle relaxant, infectious and parasitic pathologies, loss of appetite, rheumatism, intestinal cramps, headache, back pains, sexual weakness. This plant is reported to possess various biological properties like antioxidant, antimicrobial, antihyperglycemic, antileishmanial and antimalarial. These properties are due to the presence of numerous naturally occurring phytochemicals like flavonoids, alkaloids, tannins, saponins, reducting sugars, coumarins, terpenes and steroids. The present mini-review revealed that Isolona hexaloba Engl. & Diels is a good candidate for Tropical Plants Screening Research program for the development of lead compounds against genetic and parasitic diseases such as the evaluation of the anthelminthic activity.},
 year = {2018}
}

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TY - JOUR
T1 - Isolona hexaloba Engl. & Diels: Phytochemistry, Pharmacology and Future Directions: A Mini-Review
AU - Lengbiye Moke
AU - Gédéon Bongo
AU - Kongumbeti Goga
AU - Jeff Iteku
AU - Inkoto Liyongo
AU - Claudine Tshiama
AU - Ngunde Ngunde
AU - Koto-te-Nyiwa Ngbolua
AU - Pius Mpiana
Y1 - 2018/10/29
PY - 2018
N1 - https://doi.org/10.11648/j.plant.20180603.11
DO - 10.11648/j.plant.20180603.11
T2 - Plant
JF - Plant
JO - Plant
SP - 53
EP - 59
PB - Science Publishing Group
SN - 2331-0677
UR - https://doi.org/10.11648/j.plant.20180603.11
AB - The aim of this review was to provide an updated knowledge on the Phytochemistry and Pharmacognosy of Isolona hexaloba Engl. & Diels. A literature search was conducted to obtain information about the phytochemistry and pharmacognosy of Isolona hexaloba from various electronic databases (PubMed Central, PubMed, Science Direct and Google scholar). The scientific name of this plant species was used as a keyword for the search, along with the terms phytochemistry and pharmacognosy. The chemical structures of the Isolona hexaloba and Isolona genus naturally occurring compounds were drawn using ChemBioDraw Ultra 12.0 software package. The findings revealed that this plant is traditionally used as a purgative and in treating sores, smoke from the bark as a strained muscle relaxant, infectious and parasitic pathologies, loss of appetite, rheumatism, intestinal cramps, headache, back pains, sexual weakness. This plant is reported to possess various biological properties like antioxidant, antimicrobial, antihyperglycemic, antileishmanial and antimalarial. These properties are due to the presence of numerous naturally occurring phytochemicals like flavonoids, alkaloids, tannins, saponins, reducting sugars, coumarins, terpenes and steroids. The present mini-review revealed that Isolona hexaloba Engl. & Diels is a good candidate for Tropical Plants Screening Research program for the development of lead compounds against genetic and parasitic diseases such as the evaluation of the anthelminthic activity.
VL - 6
IS - 3
ER -

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Author Information

Lengbiye Moke

Department of Biology, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Gédéon Bongo

Department of Biology, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Kongumbeti Goga

Department of Biology, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Jeff Iteku

Department of Biology, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Inkoto Liyongo

Department of Biology, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Claudine Tshiama

Teaching and Administration in Nursing Care, Higher Institute of Medical Techniques, Kinshasa, Democratic Republic of the Congo
Ngunde Ngunde

Department of Biology, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Koto-te-Nyiwa Ngbolua

Department of Biology, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Pius Mpiana

Department of Chemistry, University of Kinshasa, Kinshasa, Democratic Republic of the Congo

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APA Style

Lengbiye Moke, Gédéon Bongo, Kongumbeti Goga, Jeff Iteku, Inkoto Liyongo, et al. (2018). Isolona hexaloba Engl. & Diels: Phytochemistry, Pharmacology and Future Directions: A Mini-Review. Plant, 6(3), 53-59. https://doi.org/10.11648/j.plant.20180603.11

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ACS Style

Lengbiye Moke; Gédéon Bongo; Kongumbeti Goga; Jeff Iteku; Inkoto Liyongo, et al. Isolona hexaloba Engl. & Diels: Phytochemistry, Pharmacology and Future Directions: A Mini-Review. Plant. 2018, 6(3), 53-59. doi: 10.11648/j.plant.20180603.11

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AMA Style

Lengbiye Moke, Gédéon Bongo, Kongumbeti Goga, Jeff Iteku, Inkoto Liyongo, et al. Isolona hexaloba Engl. & Diels: Phytochemistry, Pharmacology and Future Directions: A Mini-Review. Plant. 2018;6(3):53-59. doi: 10.11648/j.plant.20180603.11

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@article{10.11648/j.plant.20180603.11,
  author = {Lengbiye Moke and Gédéon Bongo and Kongumbeti Goga and Jeff Iteku and Inkoto Liyongo and Claudine Tshiama and Ngunde Ngunde and Koto-te-Nyiwa Ngbolua and Pius Mpiana},
  title = {Isolona hexaloba Engl. & Diels: Phytochemistry, Pharmacology and Future Directions: A Mini-Review},
  journal = {Plant},
  volume = {6},
  number = {3},
  pages = {53-59},
  doi = {10.11648/j.plant.20180603.11},
  url = {https://doi.org/10.11648/j.plant.20180603.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.plant.20180603.11},
  abstract = {The aim of this review was to provide an updated knowledge on the Phytochemistry and Pharmacognosy of Isolona hexaloba Engl. & Diels. A literature search was conducted to obtain information about the phytochemistry and pharmacognosy of Isolona hexaloba from various electronic databases (PubMed Central, PubMed, Science Direct and Google scholar). The scientific name of this plant species was used as a keyword for the search, along with the terms phytochemistry and pharmacognosy. The chemical structures of the Isolona hexaloba and Isolona genus naturally occurring compounds were drawn using ChemBioDraw Ultra 12.0 software package. The findings revealed that this plant is traditionally used as a purgative and in treating sores, smoke from the bark as a strained muscle relaxant, infectious and parasitic pathologies, loss of appetite, rheumatism, intestinal cramps, headache, back pains, sexual weakness. This plant is reported to possess various biological properties like antioxidant, antimicrobial, antihyperglycemic, antileishmanial and antimalarial. These properties are due to the presence of numerous naturally occurring phytochemicals like flavonoids, alkaloids, tannins, saponins, reducting sugars, coumarins, terpenes and steroids. The present mini-review revealed that Isolona hexaloba Engl. & Diels is a good candidate for Tropical Plants Screening Research program for the development of lead compounds against genetic and parasitic diseases such as the evaluation of the anthelminthic activity.},
 year = {2018}
}

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