Sansho (Japanese pepper) is a common spice widely used in Japanese cuisine. In addition, it is also an important component in Kampo medicine, such as in Daiken Chuto, which stimulates gastrointestinal motility and improves postoperative ileus. On the other hand, we previously reported that gravity stress loading produce negative effects on ileal movements. In the present study, we report changes in ileal motility after gravity-stress with and without Sansho intake in male and female rats. Ileal movements were activated by topical Acetylcholine (Ach) application, and maximum amplitudes (MA) of the evoked contraction were compared. Clear tonic patterns were observed in the ileal motility after Ach application. After short-term stress, there were no significant differences in MA between control and Sansho-intake groups in both sexes. However, after long-term stress-loading, significant enhancement of MA was observed in Sansho-intake group in males, but not in females. The present study showed that SAN affected Ach-induced ileal motility in the male, but not in the female after long-term stress loading, indicating sex differences in effects of Sansho intake. It is suggested that Sansho is more effective in males than in females to decrease negative stress response.
| Published in |
Journal of Food and Nutrition Sciences (Volume 3, Issue 3-1)
This article belongs to the Special Issue Effects of Foods on Gastrointestinal, Metabolic and Immunological Function |
| DOI | 10.11648/j.jfns.s.2015030301.13 |
| Page(s) | 9-12 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2015. Published by Science Publishing Group |
Sansho (Japanese Pepper), Ileum, Stress, Motility, Sex Difference, Rat
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APA Style
Mari Kimoto, Jorge L. Zeredo, Masato S. Ota, Zenro Nihei, Kazuo Toda. (2015). Sansho Intake Modulates Ileum Activity in Stress-loaded Rats. Journal of Food and Nutrition Sciences, 3(3-1), 9-12. https://doi.org/10.11648/j.jfns.s.2015030301.13
ACS Style
Mari Kimoto; Jorge L. Zeredo; Masato S. Ota; Zenro Nihei; Kazuo Toda. Sansho Intake Modulates Ileum Activity in Stress-loaded Rats. J. Food Nutr. Sci. 2015, 3(3-1), 9-12. doi: 10.11648/j.jfns.s.2015030301.13
AMA Style
Mari Kimoto, Jorge L. Zeredo, Masato S. Ota, Zenro Nihei, Kazuo Toda. Sansho Intake Modulates Ileum Activity in Stress-loaded Rats. J Food Nutr Sci. 2015;3(3-1):9-12. doi: 10.11648/j.jfns.s.2015030301.13
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Download@article{10.11648/j.jfns.s.2015030301.13,
author = {Mari Kimoto and Jorge L. Zeredo and Masato S. Ota and Zenro Nihei and Kazuo Toda},
title = {Sansho Intake Modulates Ileum Activity in Stress-loaded Rats},
journal = {Journal of Food and Nutrition Sciences},
volume = {3},
number = {3-1},
pages = {9-12},
doi = {10.11648/j.jfns.s.2015030301.13},
url = {https://doi.org/10.11648/j.jfns.s.2015030301.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jfns.s.2015030301.13},
abstract = {Sansho (Japanese pepper) is a common spice widely used in Japanese cuisine. In addition, it is also an important component in Kampo medicine, such as in Daiken Chuto, which stimulates gastrointestinal motility and improves postoperative ileus. On the other hand, we previously reported that gravity stress loading produce negative effects on ileal movements. In the present study, we report changes in ileal motility after gravity-stress with and without Sansho intake in male and female rats. Ileal movements were activated by topical Acetylcholine (Ach) application, and maximum amplitudes (MA) of the evoked contraction were compared. Clear tonic patterns were observed in the ileal motility after Ach application. After short-term stress, there were no significant differences in MA between control and Sansho-intake groups in both sexes. However, after long-term stress-loading, significant enhancement of MA was observed in Sansho-intake group in males, but not in females. The present study showed that SAN affected Ach-induced ileal motility in the male, but not in the female after long-term stress loading, indicating sex differences in effects of Sansho intake. It is suggested that Sansho is more effective in males than in females to decrease negative stress response.},
year = {2015}
}
TY - JOUR T1 - Sansho Intake Modulates Ileum Activity in Stress-loaded Rats AU - Mari Kimoto AU - Jorge L. Zeredo AU - Masato S. Ota AU - Zenro Nihei AU - Kazuo Toda Y1 - 2015/07/03 PY - 2015 N1 - https://doi.org/10.11648/j.jfns.s.2015030301.13 DO - 10.11648/j.jfns.s.2015030301.13 T2 - Journal of Food and Nutrition Sciences JF - Journal of Food and Nutrition Sciences JO - Journal of Food and Nutrition Sciences SP - 9 EP - 12 PB - Science Publishing Group SN - 2330-7293 UR - https://doi.org/10.11648/j.jfns.s.2015030301.13 AB - Sansho (Japanese pepper) is a common spice widely used in Japanese cuisine. In addition, it is also an important component in Kampo medicine, such as in Daiken Chuto, which stimulates gastrointestinal motility and improves postoperative ileus. On the other hand, we previously reported that gravity stress loading produce negative effects on ileal movements. In the present study, we report changes in ileal motility after gravity-stress with and without Sansho intake in male and female rats. Ileal movements were activated by topical Acetylcholine (Ach) application, and maximum amplitudes (MA) of the evoked contraction were compared. Clear tonic patterns were observed in the ileal motility after Ach application. After short-term stress, there were no significant differences in MA between control and Sansho-intake groups in both sexes. However, after long-term stress-loading, significant enhancement of MA was observed in Sansho-intake group in males, but not in females. The present study showed that SAN affected Ach-induced ileal motility in the male, but not in the female after long-term stress loading, indicating sex differences in effects of Sansho intake. It is suggested that Sansho is more effective in males than in females to decrease negative stress response. VL - 3 IS - 3-1 ER -
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